If I'm developing a client side application with heavy load, what is the most appropriate choice of Ajax framework?
I'd recommend you the JQuery. It is not just an ajax framework, it is more than that.
Client side? jQuery. Server side? Depends on your environment. Also, AJAX is not a framework per definition, but there are various libraries like jQuery which will ease the pain when using AJAX.
AJAX exists just to send some data and recieve some data from your server or some other site without forcing you to do a whole page reload. That's all about it in the nutshell.
If you're looking for a technology that will automatically place widgets on your site that use AJAX, that's a whole different story...
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