ClickOnce required to run setup?

Could anybody advise me if we need to install ClickOnce application on client's computer, if we need to run a setup file made wi开发者_开发技巧th ClickOnce?

Also, when we publish, how can we specify if we want to use ClickOnce or Windows installer?

Thanks Furqan

---

You don't need to install anything in the client if you're going to deploy your app using ClickOnce.

If you run the publish wizard, the wizard will ask you "How will the users install the application?" If you select "From a CDROM or DVDROM" option then a setup.exe will generate in the selected path.