How many millions records can Mysql reasonably deal with with .NET?

Anybody can tell his experience with MySQL and .NET dealing with millions of records ?

Would myself ne开发者_Go百科ed to be able to cope with 50 to 100 Millions records and would like to hear about how you cope with this in your precise context so that I may inspire from it.

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This question is fairly open ended...

If tuned right, mysql could deal with more than 100M records. It all depends on your indexing and table design, as well as proper server tuning and hardware.