How to remove the handler in javascript

I'm adding some document to addhandler, where this script will execute on each time on ajax call.

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But on the ajax result how can I remove the handler, where i tried using removeHandler but for the first time its getting affected.

Is any method to check whether the event is alive kill it.

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If you want to remove an event handler with Javascript, you need to unsubscribe it this way:

document.getElementById("yourelement").removeEventListener("yourEvent", yourFunction);