What tools can create 2-D and 3-D animations I can use in an iPad app?

I would like to create 2-D or 3-D animations using a tool, then use these animations in an iPad app that I'm writing. What tools exist that can create such animations?

Can any of the Adobe products crea开发者_开发百科te files which can be integrated with an iPad app? I know that Flash can be used to create animations, but support for this is limited on iOS devices.

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OpenGL can be used for 2D/3D graphics and animations and Cocos2D for 2D graphics and animations. The only thing I know about Adobe is that Flex can be used to make iPhone apps. Maybe you can import After Effects or Flash files into that?