Regex to remove non-URL friendly characters, but allow Unicode and accents

I have the following regex:

foo =开发者_高级运维 Regex.Replace(foo, @"[^a-zA-Z0-9\s-]", " ");

Currently, this removes Unicode characters. What regex can I use remove all non-URL friendly characters (i.e. : , < etc.), but allow Unicode and accented characters?

Thanks, Mark

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How about instead of using a negated class, you simply have a replacement list of the characters you dont want?

s/[:,<]*//g

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Microsoft.Security.Application.AntiXss.GetSafeHtml() solved my problem.