Store file mapping from local to cloud

In Python, what do you believe is the best way to store file mapping info from local mac开发者_高级运维hine to cloud storage?

i.e. A user has 10 files in 3 different folders on his local machine. They are also stored on a cloud storage, each identify by URL or other descriptors.

Best way - in terms of scallability, search/insert efficiency, etc.

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You can either use the rsync program, or the rsync algorithm implemented in Python. Assumably you can have access to the remote files over something that looks like a file system, like WebDAV.

Best